Document Type : Original Article
Authors
1
PhD Student, Department of Microbiology ,Tehran North Branch, Islamic Azad University ,Tehran, Iran Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences,Khorramabad, Iran
2
Expert Laboratory Khorram Abad Shohada-ye-Ashayer Hospital, Khorramabad, Iran
3
MSC Student, Department of Microbiology ,Borujerd branch , Islamic Azad University, Borujerd, Iran
4
MSC Studentof Epidemiology, Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran
5
PhD Student, Student Research Committee,Department of Microbiology ,Cellular and Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran
Abstract
Background and Aims: Staphylococci, Enterobacteriaceae family, Pseudomonas and Enterococci are common causes of blood infections. Many of these bacterial factors are resistant to different antibiotic groups. Therefore, this study aimed to determine the antibiotic susceptibility pattern in bacterial agents of blood infections isolated from patients in Shohada Hospital in Khorramabad during 2016 - 2017.
Materials and Methods: : A total of 91 bacteria isolates were isolated from blood cultures in Khorramabad Shohada Hospital and then studied by standard laboratory tests. Antibiotic susceptibility test was performed by disks diffusion method according CLSI. Data were analyzed using STATA-12 software.
Results: The high frequencies were related to E. coli and Staphylococcus. E. coli showed the highest resistance to ceftriaxone, gentamycin and Staphylococcusto clindamycin, cefoxitin, this suggests an outbreak of methicillin-resistant staphylococcus (MRSA), and the least resistance to imipenem.
Conclusion: The results of this study were consistent with other studies, and antimicrobial resistance patterns suggest increase in these bacteria. In addition, the best antibiotic for the treatment of staphylococcal coagulase negative was vancomycin and for other infections was imipenem. In order to prevent cross-contamination, effective monitoring and surveillance systems are needed for controlling hospital infections due to multi-drug resistant MRSA.
Keywords
Main Subjects
)