نویسندگان
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Background and Purpose:
Dysmenorrhea is one the most common gynecological disorders, prevalent in more than 50% of women, and affects the personal and social life with a further effect on the loss of more than millions of work hours. In addition to the conventional chemical drugs, the use of complementary and alternative medicine (CAM) is on the rise. The aim of the present study is review the effects of chemical drugs and CAM in the treatment of Dysmenorrhea.
Methods and Materials:
The present study was collected by electronic and manual search methods. 41 articles in both English and Persian were obtained from SciencesDirect, PubMed, inlm.org, sid.ir, as well as classical textbooks in the field. Results:
The major cause of primary Dysmenorrhea is an increase in the synthesis of prostaglandin, vasopressin and materials synthesized from phospholipids (such as thromboxan A2 and prostacyclin), where PGF2a and PGE2 have the most significant roles and are secreted from the endometrium during menses. Following the constant stimulation of endometrium by estrogen and progesterone, production of PG increases. Contractions caused by PG will produce pains with colic and spasmodic nature as well as pains such as labor throes in the abdomen, characterized by Dysmenorrhea. Accordingly, the mechanism of drugs effective against Dysmenorrhea includes controlling the PG synthesis and other metabolites. Conclusion:
NASAID and OCS reduce or eliminate the symptoms of Dysmenorrhea by inhibiting or reducing the synthesis of prostaglandin. In addition to these drugs, the use of complements such as Vit A, B1, B6, Zinc, Omega 3 and Mg as well as herbal medicine can reduce the menstrual pains, which in many cases come up to be equally effective as chemical drugs are. Local application of heat, biofeedback, and tranquilizing techniques as well as regular exercise will all lead to pain alleviation
کلیدواژهها [English]
)